Browsing by Author "Yildirim, Malik Ejder"
Now showing items 1-9 of 9
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The association between methylene-tetrahydrofolate reductase gene polymorphism and lung cancer risk
Arslan, Sulhattin; Karadayi, Sule; Yildirim, Malik Ejder; Ozdemir, Ozturk; Akkurt, Ibrahim (SPRINGER, 2011)This study aimed to determine the relation between methylene-tetrahydrofolate reductase (MTHFR) gene polymorphism and lung cancer risk and the frequency of this polymorphism. The study involved 64 lung cancer patients (the ... -
The Association of Plasminogen Activator Inhibitor Type 1 (PAI-1) Level and PAI-1 4G/5G Gene Polymorphism with the Formation and the Grade of Endometrial Cancer
Yildirim, Malik Ejder; Karakus, Savas; Kurtulgan, Hande Kucuk; Kilicgun, Hasan; Ersan, Serpil; Bakir, Sevtap (SPRINGER/PLENUM PUBLISHERS, 2017)Plasminogen activator inhibitor type 1 (PAI-1) is a serine protease inhibitor (Serpine 1), and it inhibits both tissue plasminogen activator and urokinase plasminogen activator which are important in fibrinolysis. We aimed ... -
Bcii-RFLP profiles for serum amiloid A1 and mutated MEFV gene prevalence in chronic renal failure patients requiring long-term hemodialysis
Ozdemir, Ozturk; Kayatas, Mansur; Cetinkaya, Selma; Yildirim, Malik Ejder; Silan, Fatma; Kurtulgan, Hande Kucuk; Koksal, Binnur; Urfali, Mine; Candan, Ferhan (TAYLOR & FRANCIS LTD, 2015)Background and aim: There is an increased mortality risk in long-term hemodialysis patients of renal failure due to the chronic inflammation. The relationship between the chronic renal failure (CRF) and the role of familial ... -
A case of weill-marchesani syndrome with a novel mutation and vitamin d deficiency
Yildirim, Malik Ejder; Vural, Ayse; Kurtulgan, Hande Kucuk; Kilicgun, Hasan; Baser, Burak (DERMAN MEDICAL PUBL, 2018)Weill-Marchesani syndrome is an inherited connective tissue disorder. It is characterized by various ocular abnormalities and some skeletal problems. It is rarely seen in the world, but the clinical complications are ... -
A possible interaction o TIMP-1 and TSP-1 with familial mediterranean fever
Yildirim, Malik Ejder; Kurtulgan, Hande Kucuk; Kilicgun, Hasan; Bakir, Deniz; Ersan, Sepil (DERMAN MEDICAL PUBL, 2019)Aim: Matrix metalloproteinases (MMPs) may influence many biological and pathological processes including inflammatory responses. Thrombospondins (TSP) are a glycoprotein group of the extracellular matrix. In this study, ... -
Recombinant chromosome with partial 14 q trisomy due to maternal pericentric inversion
Kurtulgan, Hande Kucuk; Ozer, Leyla; Yildirim, Malik Ejder; Unsal, Evrim; Aktuna, Suleyman; Baltaci, Volkan; Akkus, Nejmiye; Sezgin, Ilhan (BIOMED CENTRAL LTD, 2015)Background: 14q duplications caused by parental pericentric inversion of chromosome 14 are rarely reported and no clear genotype-phenotype correlation has been determined yet. Case Presentation: Here we reported a 7 years ... -
Role of MTHFR gene polymorphisms, serum tissue inhibitor of metalloproteinases-1, thymus chemokine-1 and thrombospondin-1 in endometrial cancer
Yildirim, Malik Ejder; Kilicgun, Hasan; Kurtulgan, Hande Kucuk; Karakus, Savas; Ersan, Serpil; Bakir, Sevtap; Sezgin, Ilhan (E-CENTURY PUBLISHING CORP, 2016)The aim of this study was to evaluate the relationship between the MTHFR gene variants (677 C -> T and 1298 A -> C), serum tissue metalloproteinases inhibitor (TIMP-1), thrombospondin-1 (TSP-1), thymus chemokine-1 (TCK-1) ...